Wu Junxiang, Deng Liyuan, He Zhencen, et al. Effect of different physics lists in Monte Carlo simulation of proton boron capture therapy[J]. High Power Laser and Particle Beams. doi: 10.11884/HPLPB202436.240019
Citation:
Wu Junxiang, Deng Liyuan, He Zhencen, et al. Effect of different physics lists in Monte Carlo simulation of proton boron capture therapy[J]. High Power Laser and Particle Beams. doi: 10.11884/HPLPB202436.240019
Wu Junxiang, Deng Liyuan, He Zhencen, et al. Effect of different physics lists in Monte Carlo simulation of proton boron capture therapy[J]. High Power Laser and Particle Beams. doi: 10.11884/HPLPB202436.240019
Citation:
Wu Junxiang, Deng Liyuan, He Zhencen, et al. Effect of different physics lists in Monte Carlo simulation of proton boron capture therapy[J]. High Power Laser and Particle Beams. doi: 10.11884/HPLPB202436.240019
Key Laboratory of Radiation Physics and Technology of the Ministry of Education/Institute of Nuclear Science and Technology, Sichuan University, Chengdu 610064, China
2.
Radiation Oncology Department Sichuan Cancer Hospital and Institute, Affiliated Cancer Hospital of University of Electronic Science and Technology of China, Chengdu 610041, China
To compare the effects of different physics lists on the dose of proton boron capture therapy (PBCT) by Monte Carlo simulation Geant4. Geant4 was used to establish PBCT model with different three physics lists (FTFP, QBBC and QGSP). Compared the dose distribution of three physics lists with and without boron using an 80 MeV proton beam, as well as the nuclear reaction product data of a 3 MeV proton beam bombards pure boron. There is no significant difference in the dose distribution of the three physics lists in the water phantom with and without boron, and the consistency of the different physics models PDD’s curves are good. The PBCT nuclear reaction products obtained from FTFP physics list are significantly less than those obtained from QBBC and QGSP physics lists. The yields, mean energies and energy ranges of the alpha particles obtained from the QGSP physics list are more consistent with the actual situation than that of the QBBC physics list. The QGSP physics list in Geant4 is more suitable for MC simulation studies of PBCT, after a comprehensive evaluation of the inelastic scattering models used by the three physics lists and the simulated nuclear reaction data.
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