The numerical simulations of high voltage pulsed power conditioning system (inductive storage /opening switches) are given in this paper. According the different initial energy, the capacitor model and simple MFCG model are computed. For the second model, two cases –not carrying opening switches load and carrying opening switches load are considered, the results show that the current will change 20% ~31%. In the capacitor model, the affection of load, initial charging voltage, inductive storage et al are considered. By using the numerical results that only the running parameters in the system are optimized, some effective output results can be got possible.