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基于EBT3胶片开展电子FLASH放疗剂量测量研究

王诗岚 羊奕伟 程德琪 唐镭迅 吴岱

王诗岚, 羊奕伟, 程德琪, 等. 基于EBT3胶片开展电子FLASH放疗剂量测量研究[J]. 强激光与粒子束. doi: 10.11884/HPLPB202436.240095
引用本文: 王诗岚, 羊奕伟, 程德琪, 等. 基于EBT3胶片开展电子FLASH放疗剂量测量研究[J]. 强激光与粒子束. doi: 10.11884/HPLPB202436.240095
Wang Shilan, Yang Yiwei, Cheng Deqi, et al. Study of electron FLASH radiotherapy dose measurement based on EBT3 film[J]. High Power Laser and Particle Beams. doi: 10.11884/HPLPB202436.240095
Citation: Wang Shilan, Yang Yiwei, Cheng Deqi, et al. Study of electron FLASH radiotherapy dose measurement based on EBT3 film[J]. High Power Laser and Particle Beams. doi: 10.11884/HPLPB202436.240095

基于EBT3胶片开展电子FLASH放疗剂量测量研究

doi: 10.11884/HPLPB202436.240095
基金项目: 国家自然科学基金项目(12375318)
详细信息
    作者简介:

    王诗岚,wangshilan2024@163.com

    通讯作者:

    羊奕伟,winfield1920@126.com

    吴 岱,wudai04@163.com

  • 中图分类号: R144.1

Study of electron FLASH radiotherapy dose measurement based on EBT3 film

  • 摘要: 闪光放疗使用超高剂量率在毫秒时间内将剂量全部注入靶区,其超高剂量率使现有的在线剂量计基本失效,目前通常使用辐射显色胶片来测量剂量。基于中国工程物理研究院应用电子学研究所研制的电子加速器搭建了电子FLASH放疗平台,基于EBT3胶片的快速读出方法,研究了此平台的剂量率范围及剂量分布。实验结果表明,EBT3胶片的快速读出方法可用于电子FLASH放疗的剂量测量,在源皮距100 cm及深度1 cm处剂量率在240~290 Gy/s之间;电子束到达模体表面的平均能量的波动会导致靶区约±5%的剂量波动;面剂量分布满足平坦性在±5%以内和对称性在±3%以内的要求。
  • 图  1  电子FLASH辐照平台示意图(俯视图)

    Figure  1.  Schematic diagram of electron FLASH radiotherapy platform (top view)

    图  2  胶片标定结果

    Figure  2.  Film calibration result

    图  3  不同标定曲线之间测量剂量的相对偏差

    Figure  3.  Relative deviation in measured dose between different calibration curves

    图  4  不同剂量曲线的剂量分布测量结果

    Figure  4.  Measurement results of dose distribution for different dose curves

    图  5  电子束剂量分布特征

    Figure  5.  Electron beam dose distribution characteristics

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出版历程
  • 收稿日期:  2024-03-14
  • 修回日期:  2024-09-14
  • 录用日期:  2024-09-02
  • 网络出版日期:  2024-09-23

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