Design of dose simulation system for BNCT based on MeVisLab and OpenMC

Yang Xunwu; Lu Peng; Wang Shengzhe; Li Jia; Jiang Wei; Liang Lizhen

doi:10.11884/HPLPB202537.250246

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Article Navigation > High Power Laser and Particle Beams > 2025 > Accepted Manuscript

Yang Xunwu, Lu Peng, Wang Shengzhe, et al. Design of dose simulation system for BNCT based on MeVisLab and OpenMC[J]. High Power Laser and Particle Beams. doi: 10.11884/HPLPB202537.250246

Citation:

Yang Xunwu, Lu Peng, Wang Shengzhe, et al. Design of dose simulation system for BNCT based on MeVisLab and OpenMC[J]. High Power Laser and Particle Beams. doi: 10.11884/HPLPB202537.250246

Yang Xunwu, Lu Peng, Wang Shengzhe, et al. Design of dose simulation system for BNCT based on MeVisLab and OpenMC[J]. High Power Laser and Particle Beams. doi: 10.11884/HPLPB202537.250246

Citation:

Yang Xunwu, Lu Peng, Wang Shengzhe, et al. Design of dose simulation system for BNCT based on MeVisLab and OpenMC[J]. High Power Laser and Particle Beams. doi: 10.11884/HPLPB202537.250246

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Design of dose simulation system for BNCT based on MeVisLab and OpenMC

doi: 10.11884/HPLPB202537.250246

1.
School of Computer Science and Engineering, Anhui University of Science and Technology, Huainan 232001, China
2.
Institute of Energy, Hefei Comprehensive National Science Center (Anhui Energy Laboratory, Hefei 230031, China
3.
School of Nuclear Science and Technology, University of Science and Technology of China, Hefei 230026, China

Received Date: 2025-07-30
Accepted Date: 2025-09-09
Rev Recd Date: 2025-09-09

Available Online: 2025-09-16

Abstract

Abstract

Background
Boron neutron capture therapy (BNCT) dose simulation is the cornerstone of equipment development, drug iteration and clinical trials.
Purpose
To meet the need for BNCT dose simulation and analysis based on clinical CT, we propose and build a brand-new BNCT dose simulation system.
Methods
Inside the medical-image platform MeVisLab we complete DICOM registration, target delineation and RTStruct/RTDose interfaces; the open-source Monte Carlo code OpenMC is used as the engine to execute neutron-transport simulation, realizing HU-to-material mapping and variable-mesh calculation.
Results
Validation with clinical CT data simulated by the system shows that at 22 cm depth in the tumour target the boron dose accounts for 80.9% of the total dose.
Conclusions
Developed within weeks and with low licence cost, the system provides an efficient calculation tool for BNCT dose simulation and a reference framework for BNCT dose simulation in research and education.
- boron neutron capture therapy,
- dose simulation system,
- MeVisLab,
- OpenMC,
- Monte Carlo simulation

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References(19)

References

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