The influence of laser entrance holes?LEHs) radius on the capsule irradiation non-uniformity in cylindrical hohlraum has been studied. It is found that the influence of LEHs at on 2 order irradiation non-uniformity can be described by a family of curves that originate from a fixed point determined by position of laser spots but had nothing to do with LEHs, and that the radius of LEHs influence the grade of non-uniformity curve. The larger the radius is, the larger the grade of non-uniformity curve is. A semirandom simulation method was used to calculate the influence of LEHs on the capsule irradiation non-uniformity when other geometrical factors are given. Fitted the results, a linear relation between irradiation non-uniformity and radius of LEHs was found.