For Ni-like ions with nuclear charge Ｚ　from 47 to 75 and Ｚ =41, 79 elements, which are suitable for use as the actuating medium in X-ray laser research,energy structures and atomic process parameters are calculated systematically. By comparing and fitting to some experimental results, the calculated wavelengths are corrected, and experimental accuracy has been obtained for all the ions considered. The dependence of laser line oscillator strength on nuclear charge has been illustrated. According to the parameters of Ni-like Nd ions, an explanation is given about why some important spectrum lines can't be amplified．