Abstract: Aiming at the front door coupling effect of high-power microwave on millimeter wave fuze, the electromagnetic simulation software was used to irradiate a certain millimeter wave FM continuous wave fuze model, and the joint simulation was carried out with the front-end limiting circuit of the fuze. On this basis, orthogonal experiments are designed to analyze the influence level of signal parameters. When the high-power microwave signal frequency is aligned with the fuze working frequency, the simulation results show that the maximum coupling voltage at the end of the antenna can reach 188 V when the peak radiation field intensity is 60 kV/m. When the peak radiation field intensity is 40 kV/m, changing the characteristic parameters of the radiation signal and finds that the long pulse width signal is more likely to cause the thermal breakdown effect of the limiter; the rising time of the signal will affect the end of the antenna. When the peak value and pulse width of the coupled voltage waveform are fixed, the spike leakage voltage caused by the input signal with rise time of 5 ns is about 5.94 V, while the spike leakage voltage is 18.4 V when rise time is 0.1 ns, and the limiting circuit reaches saturation state faster. The orthogonal experiment shows that the spike leakage peak voltage is most affected by the rise time of the signal, and the signal peak is the largest, meanwhile the value has the second effect on it.