Abstract: Considering the neutral particle beams can help cleaning effect in space debris in low-Earth orbit and their potential application prospects in space exploration, this paper analyzes several major mechanisms that cause beam energy loss and density loss during the long-range transmission of neutral particle beams in sub-orbital space, and focuses on analyzing the effect of stripping effects on beam loss. The neutral beam stripping effects include self-stripping effects caused by collisions of stripped particles with beam particles and stripping effects caused by collisions of beam particles with atmospheric particles. Based on the equation that the beam density changes with the propagation distance, this paper introduces a geometric factor to characterize the intensity of the self-stripping effect of the beam, and derives the functional relationship between the transmission distance and the geometric factor. By normalizing the transmission distance under a certain particle survival ratio, it evaluates the relative importance of the effect of beam self-stripping on the transmission distance in the long-range transmission of neutral beams. The results show that at a fixed height, when the neutral beam density is greater than the density of air particles, the self-stripping effect will be very strong. With the increase of the transmission height, even if the beam density and the air density decrease at the same time with the same order of magnitude, the effect of self stripping on the transmission distance will increase with a large geometric factor.