Abstract: The gain of silicon photomultiplier tube will drift greatly due to temperature variation, which will affect the gain accuracy of silicon photomultiplier tube. To realize that silicon photomultiplier tube gain does not change greatly with temperature variation, an automatic gain correction system for silicon photomultiplier tube is designed, including the design of a high voltage power supply and an acquisition system based on single chip microcomputer.The high voltage module can accurately operate in the temperature range of −10 ℃ to 60 ℃, and the power noise is about 30 mV, which can meet the requirements of silicon photomultiplier tube performance testing.Through frequency sweep test and laser irradiation test, the acquisition system can better pass the 60 MHz AC signal, and transform the optical signal into a more obvious electrical signal.The system provides a working voltage and acquisition circuit to Jingbon Compony’s silicon photomultiplier tube array JARY-TP3050-8X8C.