Abstract: Vacuum arc neutron tube is a neutron source with high pulse neutron yield. It is widely used in oil logging, element activation analysis and other fields. One of the typical characteristics of vacuum arc neutron tube is large discharge arc current and short pulse width. A set of vacuum arc discharge and extraction power supply with large current is developed, including trigger module, main arc module and extraction module. The trigger module uses LRC discharge mode, and the peak output voltage is 5 kV. The arc module uses LRCD half-cycle discharge mode to generate the main arc current. The peak current is 600 A, and the half-height width is about 0.5 μs. The extraction module uses a multi-voltage rectifier circuit to rectify AC high-voltage into the required high-voltage DC, with an output voltage of 120 kV and a load of 2 A. The simulation model is established according to the design scheme, and the simulation results show that the power supply can output the set electrical parameters well. Finally, a high-current vacuum arc discharge and extraction power supply is fabricated. The test results show that the output parameters of the power supply are consistent with the design values, and the power supply can be used to drive a vacuum arc neutron tube.