Abstract: This paper introduces a single-shot compact pulsed power source (PPS) based on an explosively driven flux compression generator (FCG) for some off-grid applications. The PPS was designed to rapidly charge a capacitive load of 65 pF to hundreds of kilo volts. Considering the impedance mismatch between the FCG and the load, a power conditioning module mainly consisting of an intermediate capacitor, an electro-explosive opening switch (EEOS) and an air-cored transformer was employed. This paper presents the design and experimental results in detail. Besides, it analyzes the experimental results and discusses the possible improvements in future. It is indicated that the capacitive load was successfully charged to -352 kV with a rising time of about 10 ns.